CD32
E747115
CD32 is a low-affinity Fc gamma receptor (FcγRII) found on various immune cells that plays a key role in modulating antibody-dependent immune responses.
All labels observed (1)
| Label | Occurrences |
|---|---|
| CD32 canonical | 1 |
How this entity was disambiguated
This entity first appeared as the object of triple T8632656 — resolving that mention is where its identity was fixed. The disambiguator weighed these candidate entities and picked the highlighted one (or “None”, minting a new entity). This is how homonymy is resolved: the same surface form can point to different entities.
NED1
Entity disambiguation (via context triple)
gpt-5-mini-2025-08-07
Target entity: CD32 Context triple: [AGA, usedIn, CD32]
-
A.
CD6
CD6 is the commonly used abbreviation for Manhattan Community District 6, a local administrative area on the East Side of Manhattan in New York City.
-
B.
M32
M32 is a compact dwarf elliptical galaxy that orbits the Andromeda Galaxy within the Local Group.
-
C.
CA-32
CA-32 is the hull classification symbol for USS New Orleans, a U.S. Navy heavy cruiser that saw extensive service during World War II.
-
D.
M-32
M-32 is an east–west state trunkline highway in northern Michigan that connects several inland communities across the northern Lower Peninsula.
-
E.
A92
A92 is a major trunk road in eastern Scotland that runs along the coast, connecting several key towns and cities including Dundee and Aberdeen.
- F. None of above. chosen
- G. Unsure - the case is ambiguous/there is not enough information to decide.
NED2
Entity disambiguation (via description)
gpt-5-mini-2025-08-07
Target entity: CD32 Target entity description: CD32 is a low-affinity Fc gamma receptor (FcγRII) found on various immune cells that plays a key role in modulating antibody-dependent immune responses.
-
A.
CD6
CD6 is the commonly used abbreviation for Manhattan Community District 6, a local administrative area on the East Side of Manhattan in New York City.
-
B.
M32
M32 is a compact dwarf elliptical galaxy that orbits the Andromeda Galaxy within the Local Group.
-
C.
CA-32
CA-32 is the hull classification symbol for USS New Orleans, a U.S. Navy heavy cruiser that saw extensive service during World War II.
-
D.
M-32
M-32 is an east–west state trunkline highway in northern Michigan that connects several inland communities across the northern Lower Peninsula.
-
E.
A92
A92 is a major trunk road in eastern Scotland that runs along the coast, connecting several key towns and cities including Dundee and Aberdeen.
- F. None of above. chosen
Statements (50)
| Predicate | Object |
|---|---|
| instanceOf |
Fc gamma receptor
ⓘ
cell surface receptor ⓘ immune receptor ⓘ protein ⓘ |
| bindsTo | Fc region of IgG ⓘ |
| encodedBy |
FCGR2A
ⓘ
FCGR2B ⓘ
linked to:
Fc gamma receptor II
FCGR2C ⓘ
linked to:
Fc gamma receptor II
|
| expressedOn |
B cells
ⓘ
linked to:
B lymphocytes
basophils ⓘ dendritic cells ⓘ eosinophils ⓘ macrophages ⓘ mast cells ⓘ monocytes ⓘ neutrophils ⓘ platelets ⓘ some NK cells ⓘ |
| hasAffinityFor | IgG ⓘ |
| hasAffinityType | low-affinity ⓘ |
| hasAlternativeName |
Fc gamma receptor II
ⓘ
FcγRII ⓘ FcγRII receptor ⓘ
linked to:
Fc gamma receptor II
|
| hasBiologicalProcess |
B cell activation regulation
ⓘ
antibody-dependent immune response ⓘ antigen presentation modulation ⓘ immune complex clearance ⓘ inflammatory response modulation ⓘ phagocytosis regulation ⓘ |
| hasDomain |
cytoplasmic tail
ⓘ
extracellular Ig-like domain ⓘ transmembrane domain ⓘ |
| hasIsoform |
activating FcγRIIA
ⓘ
activating FcγRIIC ⓘ inhibitory FcγRIIB ⓘ |
| hasMolecularFunction |
IgG binding
ⓘ
immune receptor activity ⓘ |
| hasSignalingMotif |
ITAM (in FcγRIIA and FcγRIIC)
ⓘ
ITIM (in FcγRIIB) ⓘ |
| hasSubtype |
CD32A
ⓘ
CD32B ⓘ CD32C ⓘ |
| involvedIn |
allergic inflammation regulation
ⓘ
autoimmune disease pathogenesis ⓘ |
| locatedIn | plasma membrane ⓘ |
| memberOf |
Fc gamma receptor family
ⓘ
linked to:
Fc gamma receptor II
immunoglobulin superfamily ⓘ |
| modulates |
antibody-dependent cellular cytotoxicity
ⓘ
antibody-dependent cellular phagocytosis ⓘ |
| species | Homo sapiens ⓘ |
How these facts were elicited
The pipeline generated the facts above by prompting gpt-5.1 with this entity's name + description and the instruction below.
Instruction
You are a knowledge base construction expert. Given a subject entity and a description of it, return factual statements that you know for the subject as a JSON list of dictionaries(triples), where keys must be "subject", "predicate" and "object". The number of facts may be very high, between 25 to 50 or more, for very popular subjects. For less popular subjects, the number of facts can be very low, like 5 or 10. # Requirements - If you don't know the subject at all, return an empty list. - If the subject is not a named entity, return an empty list. - Include at least one triple where predicate is "instanceOf". - Do not get too wordy. - Separate several objects into multiple triples with one object.
Input
Subject: CD32 Description of subject: CD32 is a low-affinity Fc gamma receptor (FcγRII) found on various immune cells that plays a key role in modulating antibody-dependent immune responses.
Referenced by (1)
Full triples — surface form annotated when it differs from this entity's canonical label.