Haldane’s cost of selection
E725887
Haldane’s cost of selection is a population genetics concept quantifying the reproductive burden and time required for natural selection to replace one gene variant with a fitter alternative in a population.
All labels observed (1)
| Label | Occurrences |
|---|---|
| Haldane’s cost of selection canonical | 1 |
How this entity was disambiguated
This entity first appeared as the object of triple T8321188 — resolving that mention is where its identity was fixed. The disambiguator weighed these candidate entities and picked the highlighted one (or “None”, minting a new entity). This is how homonymy is resolved: the same surface form can point to different entities.
NED1
Entity disambiguation (via context triple)
gpt-5-mini-2025-08-07
Target entity: Haldane’s cost of selection Context triple: [Haldane’s dilemma, relatedConcept, Haldane’s cost of selection]
-
A.
Fisher's fundamental theorem of natural selection
Fisher's fundamental theorem of natural selection is a key principle in evolutionary biology stating that the rate of increase in fitness of a population is proportional to its genetic variance in fitness.
-
B.
The Roles of Mutation, Inbreeding, Crossbreeding and Selection in Evolution
"The Roles of Mutation, Inbreeding, Crossbreeding and Selection in Evolution" is a landmark 1932 paper by geneticist Sewall Wright that helped establish the theoretical foundations of population genetics and modern evolutionary theory.
-
C.
The Genetical Theory of Natural Selection
The Genetical Theory of Natural Selection is a landmark 1930 book that founded modern evolutionary genetics by mathematically uniting Mendelian inheritance with Darwinian natural selection.
-
D.
Evolution in Mendelian Populations
"Evolution in Mendelian Populations" is a foundational 1931 paper by Sewall Wright that introduced key concepts of population genetics, including genetic drift, inbreeding, and the shifting balance theory of evolution.
-
E.
Genetics of the Evolutionary Process
Genetics of the Evolutionary Process is a seminal work in evolutionary biology that synthesizes genetic principles with natural selection to explain how evolutionary change occurs within and between populations.
- F. None of above. chosen
- G. Unsure - the case is ambiguous/there is not enough information to decide.
NED2
Entity disambiguation (via description)
gpt-5-mini-2025-08-07
Target entity: Haldane’s cost of selection Target entity description: Haldane’s cost of selection is a population genetics concept quantifying the reproductive burden and time required for natural selection to replace one gene variant with a fitter alternative in a population.
-
A.
Fisher's fundamental theorem of natural selection
Fisher's fundamental theorem of natural selection is a key principle in evolutionary biology stating that the rate of increase in fitness of a population is proportional to its genetic variance in fitness.
-
B.
The Roles of Mutation, Inbreeding, Crossbreeding and Selection in Evolution
"The Roles of Mutation, Inbreeding, Crossbreeding and Selection in Evolution" is a landmark 1932 paper by geneticist Sewall Wright that helped establish the theoretical foundations of population genetics and modern evolutionary theory.
-
C.
The Genetical Theory of Natural Selection
The Genetical Theory of Natural Selection is a landmark 1930 book that founded modern evolutionary genetics by mathematically uniting Mendelian inheritance with Darwinian natural selection.
-
D.
Evolution in Mendelian Populations
"Evolution in Mendelian Populations" is a foundational 1931 paper by Sewall Wright that introduced key concepts of population genetics, including genetic drift, inbreeding, and the shifting balance theory of evolution.
-
E.
Genetics of the Evolutionary Process
Genetics of the Evolutionary Process is a seminal work in evolutionary biology that synthesizes genetic principles with natural selection to explain how evolutionary change occurs within and between populations.
- F. None of above. chosen
Statements (37)
| Predicate | Object |
|---|---|
| instanceOf |
evolutionary biology concept
ⓘ
population genetics concept ⓘ |
| addresses |
constraints on simultaneous substitutions at many loci
ⓘ
trade-off between selection intensity and population viability ⓘ |
| alsoKnownAs |
cost of natural selection
ⓘ
substitutional load ⓘ |
| appliesTo | replacement of one gene variant by a fitter alternative ⓘ |
| assumes | finite reproductive excess in populations ⓘ |
| concerns |
limits on speed of natural selection
ⓘ
rate of adaptive evolution ⓘ |
| definedBy | J. B. S. Haldane NERFINISHED ⓘ |
| field |
evolutionary theory
ⓘ
population genetics ⓘ |
| historicalContext | mid-20th century population genetics ⓘ |
| implies | upper bound on rate of gene substitutions ⓘ |
| influenced |
later work on genetic load
ⓘ
theoretical limits on adaptive evolution in large populations ⓘ |
| involves |
allele frequency change over time
ⓘ
mortality due to selection ⓘ population size ⓘ reproductive rate ⓘ selection coefficient ⓘ |
| mathematicallyCharacterizedAs | cumulative number of selective deaths needed for allele fixation ⓘ |
| quantifies |
number of selective deaths required for gene substitution
ⓘ
reproductive burden of selection ⓘ time required for a fitter allele to replace a less fit allele ⓘ |
| relatedConcept |
Haldane’s dilemma
NERFINISHED
ⓘ
adaptive substitution rate ⓘ genetic drift ⓘ genetic substitution ⓘ selective sweep ⓘ |
| relatesTo |
fixation of advantageous alleles
ⓘ
genetic load ⓘ selective deaths ⓘ |
| usedIn |
arguments about limits to adaptive evolution
ⓘ
debates on feasibility of rapid evolution ⓘ discussions of molecular evolution rates ⓘ |
How these facts were elicited
The pipeline generated the facts above by prompting gpt-5.1 with this entity's name + description and the instruction below.
Instruction
You are a knowledge base construction expert. Given a subject entity and a description of it, return factual statements that you know for the subject as a JSON list of dictionaries(triples), where keys must be "subject", "predicate" and "object". The number of facts may be very high, between 25 to 50 or more, for very popular subjects. For less popular subjects, the number of facts can be very low, like 5 or 10. # Requirements - If you don't know the subject at all, return an empty list. - If the subject is not a named entity, return an empty list. - Include at least one triple where predicate is "instanceOf". - Do not get too wordy. - Separate several objects into multiple triples with one object.
Input
Subject: Haldane’s cost of selection Description of subject: Haldane’s cost of selection is a population genetics concept quantifying the reproductive burden and time required for natural selection to replace one gene variant with a fitter alternative in a population.
Referenced by (1)
Full triples — surface form annotated when it differs from this entity's canonical label.