Hugh McDevitt

E431503

Hugh McDevitt is an immunologist renowned for his pioneering work on the genetic control of the immune response and the role of major histocompatibility complex (MHC) molecules in disease susceptibility.

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Hugh McDevitt canonical 1

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Predicate Object
instanceOf human
immunologist
awardReceived Gairdner Foundation International Award NERFINISHED
Lasker Award for Basic Medical Research NERFINISHED
contributedTo concept that MHC molecules present antigenic peptides to T cells
demonstration that MHC genes control immune response to specific antigens
mapping of immune response genes
understanding of MHC restriction
educatedAt Harvard University
Stanford University School of Medicine NERFINISHED
fieldOfWork immunogenetics
immunology
hasAcademicDiscipline medicine
microbiology and immunology
hasInfluenced development of MHC-based disease association studies
modern immunogenetics
understanding of autoimmune disease pathogenesis
influenced subsequent research on HLA-disease associations in humans
influencedBy Baruj Benacerraf NERFINISHED
knownFor genetic control of the immune response
immune response genes (Ir genes)
role of major histocompatibility complex molecules in immune responses
studies of disease susceptibility linked to MHC
languageOfWorkOrName English
memberOf National Academy of Sciences
surface form: National Academy of Sciences of the United States of America
nationality American
notableConcept genetic control of antibody specificity
immune response genes linked to MHC
occupation immunologist
positionHeld chair of the Department of Microbiology and Immunology at Stanford University
professor at Stanford University
researchFocus association of MHC alleles with autoimmune disease risk
genetic basis of immune responsiveness
mechanisms of antigen presentation
studied T-cell recognition of antigen
association between H-2 complex and immune responsiveness in mice
genetic control of immune responses to synthetic polypeptide antigens
genetic regulation of antibody responses
major histocompatibility complex
workLocation Stanford University NERFINISHED

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Santa J. Ono doctoralAdvisor Hugh McDevitt