beta-amyloid
E1583704
UNEXPLORED
Beta-amyloid is a peptide that accumulates abnormally in the brain to form plaques strongly associated with the development and progression of Alzheimer’s disease.
All labels observed (1)
| Label | Occurrences |
|---|---|
| beta-amyloid canonical | 1 |
How this entity was disambiguated
This entity first appeared as the object of triple T23399618 — resolving that mention is where its identity was fixed. The disambiguator weighed these candidate entities and picked the highlighted one (or “None”, minting a new entity). This is how homonymy is resolved: the same surface form can point to different entities.
NED1
Entity disambiguation (via context triple)
gpt-5-mini-2025-08-07
Target entity: beta-amyloid Context triple: [bapineuzumab, target, beta-amyloid]
-
A.
alpha-synuclein
Alpha-synuclein is a neuronal protein whose abnormal aggregation is a hallmark of Parkinson’s disease and related synucleinopathies.
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B.
Lewy bodies
Lewy bodies are abnormal aggregates of the protein alpha-synuclein that accumulate inside neurons and are characteristic of Parkinson’s disease and related neurodegenerative disorders.
-
C.
Alzheimer
Alzheimer is a German surname most famously associated with Alois Alzheimer, the neurologist after whom Alzheimer’s disease is named.
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D.
bapineuzumab
Bapineuzumab is a humanized monoclonal antibody that was investigated as an immunotherapy for Alzheimer’s disease by targeting beta-amyloid plaques.
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E.
Alzheimer's disease
Alzheimer's disease is a progressive neurodegenerative disorder characterized by memory loss, cognitive decline, and behavioral changes, and is the most common cause of dementia in older adults.
- F. None of above. chosen
- G. Unsure - the case is ambiguous/there is not enough information to decide.
NED2
Entity disambiguation (via description)
gpt-5-mini-2025-08-07
Target entity: beta-amyloid Target entity description: Beta-amyloid is a peptide that accumulates abnormally in the brain to form plaques strongly associated with the development and progression of Alzheimer’s disease.
-
A.
alpha-synuclein
Alpha-synuclein is a neuronal protein whose abnormal aggregation is a hallmark of Parkinson’s disease and related synucleinopathies.
-
B.
Lewy bodies
Lewy bodies are abnormal aggregates of the protein alpha-synuclein that accumulate inside neurons and are characteristic of Parkinson’s disease and related neurodegenerative disorders.
-
C.
Alzheimer
Alzheimer is a German surname most famously associated with Alois Alzheimer, the neurologist after whom Alzheimer’s disease is named.
-
D.
bapineuzumab
Bapineuzumab is a humanized monoclonal antibody that was investigated as an immunotherapy for Alzheimer’s disease by targeting beta-amyloid plaques.
-
E.
Alzheimer's disease
Alzheimer's disease is a progressive neurodegenerative disorder characterized by memory loss, cognitive decline, and behavioral changes, and is the most common cause of dementia in older adults.
- F. None of above. chosen
Referenced by (1)
Full triples — surface form annotated when it differs from this entity's canonical label.