dopamine D2 receptor
E1558307
UNEXPLORED
The dopamine D2 receptor is a G protein–coupled receptor in the brain that plays a key role in modulating dopamine signaling, influencing movement, motivation, and many psychiatric and neurological processes.
All labels observed (2)
| Label | Occurrences |
|---|---|
| dopamine D2 receptor canonical | 2 |
| D2 dopamine receptor | 1 |
How this entity was disambiguated
This entity first appeared as the object of triple T22871194 — resolving that mention is where its identity was fixed. The disambiguator weighed these candidate entities and picked the highlighted one (or “None”, minting a new entity). This is how homonymy is resolved: the same surface form can point to different entities.
NED1
Entity disambiguation (via context triple)
gpt-5-mini-2025-08-07
Target entity: dopamine D2 receptor Context triple: [thioridazine, actsOnReceptor, dopamine D2 receptor]
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A.
Dopamine
"Dopamine" is a 2015 studio album by American rock band Third Eye Blind, noted for its alternative rock sound and introspective lyrics.
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B.
CB2 receptor
The CB2 receptor is a cannabinoid receptor primarily expressed in immune and peripheral tissues, where it modulates inflammation and immune responses and serves as a key target of compounds like THC.
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C.
M2 muscarinic acetylcholine receptor
The M2 muscarinic acetylcholine receptor is a G protein–coupled receptor subtype primarily found in the heart, where it mediates parasympathetic (vagal) effects such as slowing heart rate and reducing contractility.
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D.
mu-opioid receptor
The mu-opioid receptor is a G protein–coupled receptor in the nervous system that mediates the powerful analgesic and euphoric effects of opioids as well as their major side effects, including respiratory depression and dependence.
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E.
CB1 receptor
The CB1 receptor is a G protein–coupled cannabinoid receptor in the brain and nervous system that mediates most of the psychoactive effects of cannabis.
- F. None of above. chosen
- G. Unsure - the case is ambiguous/there is not enough information to decide.
NED2
Entity disambiguation (via description)
gpt-5-mini-2025-08-07
Target entity: dopamine D2 receptor Target entity description: The dopamine D2 receptor is a G protein–coupled receptor in the brain that plays a key role in modulating dopamine signaling, influencing movement, motivation, and many psychiatric and neurological processes.
-
A.
Dopamine
"Dopamine" is a 2015 studio album by American rock band Third Eye Blind, noted for its alternative rock sound and introspective lyrics.
-
B.
CB2 receptor
The CB2 receptor is a cannabinoid receptor primarily expressed in immune and peripheral tissues, where it modulates inflammation and immune responses and serves as a key target of compounds like THC.
-
C.
M2 muscarinic acetylcholine receptor
The M2 muscarinic acetylcholine receptor is a G protein–coupled receptor subtype primarily found in the heart, where it mediates parasympathetic (vagal) effects such as slowing heart rate and reducing contractility.
-
D.
mu-opioid receptor
The mu-opioid receptor is a G protein–coupled receptor in the nervous system that mediates the powerful analgesic and euphoric effects of opioids as well as their major side effects, including respiratory depression and dependence.
-
E.
CB1 receptor
The CB1 receptor is a G protein–coupled cannabinoid receptor in the brain and nervous system that mediates most of the psychoactive effects of cannabis.
- F. None of above. chosen
Referenced by (3)
Full triples — surface form annotated when it differs from this entity's canonical label.
linked to: dopamine D2 receptor