S1P5 receptor
E1468180
UNEXPLORED
The S1P5 receptor is a G protein–coupled sphingosine-1-phosphate receptor subtype primarily expressed in the central nervous system and immune cells, where it regulates cell migration, survival, and vascular integrity.
All labels observed (1)
| Label | Occurrences |
|---|---|
| S1P5 receptor canonical | 1 |
How this entity was disambiguated
This entity first appeared as the object of triple T21057571 — resolving that mention is where its identity was fixed. The disambiguator weighed these candidate entities and picked the highlighted one (or “None”, minting a new entity). This is how homonymy is resolved: the same surface form can point to different entities.
NED1
Entity disambiguation (via context triple)
gpt-5-mini-2025-08-07
Target entity: S1P5 receptor Context triple: [fingolimod, targetsReceptor, S1P5 receptor]
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A.
S1P4 receptor
The S1P4 receptor is a G protein–coupled sphingosine-1-phosphate receptor primarily expressed in immune cells, where it regulates immune cell trafficking and function.
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B.
S1P3 receptor
The S1P3 receptor is a G protein–coupled sphingosine-1-phosphate receptor involved in regulating vascular tone, immune cell trafficking, and cardiovascular function.
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C.
CB2 receptor
The CB2 receptor is a cannabinoid receptor primarily expressed in immune and peripheral tissues, where it modulates inflammation and immune responses and serves as a key target of compounds like THC.
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D.
CB1 receptor
The CB1 receptor is a G protein–coupled cannabinoid receptor in the brain and nervous system that mediates most of the psychoactive effects of cannabis.
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E.
CCR5
CCR5 is a human cell-surface chemokine receptor best known as a key co-receptor for HIV entry into immune cells and as a target for both natural resistance and gene-editing interventions against HIV infection.
- F. None of above. chosen
- G. Unsure - the case is ambiguous/there is not enough information to decide.
NED2
Entity disambiguation (via description)
gpt-5-mini-2025-08-07
Target entity: S1P5 receptor Target entity description: The S1P5 receptor is a G protein–coupled sphingosine-1-phosphate receptor subtype primarily expressed in the central nervous system and immune cells, where it regulates cell migration, survival, and vascular integrity.
-
A.
S1P4 receptor
The S1P4 receptor is a G protein–coupled sphingosine-1-phosphate receptor primarily expressed in immune cells, where it regulates immune cell trafficking and function.
-
B.
S1P3 receptor
The S1P3 receptor is a G protein–coupled sphingosine-1-phosphate receptor involved in regulating vascular tone, immune cell trafficking, and cardiovascular function.
-
C.
CB2 receptor
The CB2 receptor is a cannabinoid receptor primarily expressed in immune and peripheral tissues, where it modulates inflammation and immune responses and serves as a key target of compounds like THC.
-
D.
CB1 receptor
The CB1 receptor is a G protein–coupled cannabinoid receptor in the brain and nervous system that mediates most of the psychoactive effects of cannabis.
-
E.
CCR5
CCR5 is a human cell-surface chemokine receptor best known as a key co-receptor for HIV entry into immune cells and as a target for both natural resistance and gene-editing interventions against HIV infection.
- F. None of above. chosen
Referenced by (1)
Full triples — surface form annotated when it differs from this entity's canonical label.