PARP2
E1425815
UNEXPLORED
PARP2 is a DNA repair enzyme in the poly(ADP-ribose) polymerase family that helps maintain genomic stability and is inhibited by certain anticancer drugs.
All labels observed (1)
| Label | Occurrences |
|---|---|
| PARP2 canonical | 1 |
How this entity was disambiguated
This entity first appeared as the object of triple T20301163 — resolving that mention is where its identity was fixed. The disambiguator weighed these candidate entities and picked the highlighted one (or “None”, minting a new entity). This is how homonymy is resolved: the same surface form can point to different entities.
NED1
Entity disambiguation (via context triple)
gpt-5-mini-2025-08-07
Target entity: PARP2 Context triple: [Lynparza, targets, PARP2]
-
A.
PARP enzymes
PARP enzymes are a family of nuclear proteins that detect DNA damage and catalyze poly(ADP-ribosyl)ation of target proteins to regulate DNA repair, genomic stability, and cell death.
-
B.
TARDBP
TARDBP is a gene encoding the TDP-43 protein, a DNA/RNA-binding protein whose abnormal aggregation is a key pathological feature in amyotrophic lateral sclerosis and related neurodegenerative diseases.
-
C.
RPAPL
RPAPL is the commonly used abbreviation for New York’s Real Property Actions and Proceedings Law, which governs legal actions involving real estate in the state.
-
D.
XPF
XPF is the CFP franc, a currency used in several French overseas collectivities in the Pacific, including French Polynesia.
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E.
DPPA
DPPA is the United Nations department responsible for conflict prevention, peacemaking, and supporting political and peacebuilding efforts worldwide.
- F. None of above. chosen
- G. Unsure - the case is ambiguous/there is not enough information to decide.
NED2
Entity disambiguation (via description)
gpt-5-mini-2025-08-07
Target entity: PARP2 Target entity description: PARP2 is a DNA repair enzyme in the poly(ADP-ribose) polymerase family that helps maintain genomic stability and is inhibited by certain anticancer drugs.
-
A.
PARP enzymes
PARP enzymes are a family of nuclear proteins that detect DNA damage and catalyze poly(ADP-ribosyl)ation of target proteins to regulate DNA repair, genomic stability, and cell death.
-
B.
TARDBP
TARDBP is a gene encoding the TDP-43 protein, a DNA/RNA-binding protein whose abnormal aggregation is a key pathological feature in amyotrophic lateral sclerosis and related neurodegenerative diseases.
-
C.
RPAPL
RPAPL is the commonly used abbreviation for New York’s Real Property Actions and Proceedings Law, which governs legal actions involving real estate in the state.
-
D.
XPF
XPF is the CFP franc, a currency used in several French overseas collectivities in the Pacific, including French Polynesia.
-
E.
DPPA
DPPA is the United Nations department responsible for conflict prevention, peacemaking, and supporting political and peacebuilding efforts worldwide.
- F. None of above. chosen
Referenced by (1)
Full triples — surface form annotated when it differs from this entity's canonical label.