ornithine cycle
E1419985
UNEXPLORED
The ornithine cycle, also known as the urea cycle, is a metabolic pathway in the liver that converts toxic ammonia into urea for safe excretion from the body.
All labels observed (1)
| Label | Occurrences |
|---|---|
| ornithine cycle canonical | 1 |
How this entity was disambiguated
This entity first appeared as the object of triple T20270654 — resolving that mention is where its identity was fixed. The disambiguator weighed these candidate entities and picked the highlighted one (or “None”, minting a new entity). This is how homonymy is resolved: the same surface form can point to different entities.
NED1
Entity disambiguation (via context triple)
gpt-5-mini-2025-08-07
Target entity: ornithine cycle Context triple: [Hans Krebs, knownFor, ornithine cycle]
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A.
Krebs cycle
The Krebs cycle is a central metabolic pathway in cellular respiration that oxidizes acetyl-CoA to produce energy-rich molecules like NADH, FADH₂, and GTP (or ATP) while releasing carbon dioxide.
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B.
kynurenine pathway
The kynurenine pathway is the primary metabolic route for tryptophan degradation, producing several bioactive metabolites involved in immune regulation, neurobiology, and redox balance.
-
C.
Preiss–Handler pathway
The Preiss–Handler pathway is a metabolic route in which cells convert nicotinic acid (niacin) into NAD+, a vital coenzyme involved in redox reactions and energy metabolism.
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D.
Calvin cycle
The Calvin cycle is the series of biochemical reactions in photosynthetic organisms that use carbon dioxide and energy-rich molecules (ATP and NADPH) to synthesize organic sugars.
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E.
kynureninase
Kynureninase is a pyridoxal phosphate-dependent enzyme that catalyzes key steps in tryptophan degradation within the kynurenine pathway, contributing to the production of NAD⁺ and other metabolites.
- F. None of above. chosen
- G. Unsure - the case is ambiguous/there is not enough information to decide.
NED2
Entity disambiguation (via description)
gpt-5-mini-2025-08-07
Target entity: ornithine cycle Target entity description: The ornithine cycle, also known as the urea cycle, is a metabolic pathway in the liver that converts toxic ammonia into urea for safe excretion from the body.
-
A.
Krebs cycle
The Krebs cycle is a central metabolic pathway in cellular respiration that oxidizes acetyl-CoA to produce energy-rich molecules like NADH, FADH₂, and GTP (or ATP) while releasing carbon dioxide.
-
B.
kynurenine pathway
The kynurenine pathway is the primary metabolic route for tryptophan degradation, producing several bioactive metabolites involved in immune regulation, neurobiology, and redox balance.
-
C.
Preiss–Handler pathway
The Preiss–Handler pathway is a metabolic route in which cells convert nicotinic acid (niacin) into NAD+, a vital coenzyme involved in redox reactions and energy metabolism.
-
D.
Calvin cycle
The Calvin cycle is the series of biochemical reactions in photosynthetic organisms that use carbon dioxide and energy-rich molecules (ATP and NADPH) to synthesize organic sugars.
-
E.
kynureninase
Kynureninase is a pyridoxal phosphate-dependent enzyme that catalyzes key steps in tryptophan degradation within the kynurenine pathway, contributing to the production of NAD⁺ and other metabolites.
- F. None of above. chosen
Referenced by (1)
Full triples — surface form annotated when it differs from this entity's canonical label.