CRM197 diphtheria protein
E1394317
UNEXPLORED
CRM197 diphtheria protein is a non-toxic mutant form of diphtheria toxin widely used as a carrier protein in conjugate vaccines to enhance immune responses to attached polysaccharide antigens.
All labels observed (1)
| Label | Occurrences |
|---|---|
| CRM197 diphtheria protein canonical | 1 |
How this entity was disambiguated
This entity first appeared as the object of triple T19772999 — resolving that mention is where its identity was fixed. The disambiguator weighed these candidate entities and picked the highlighted one (or “None”, minting a new entity). This is how homonymy is resolved: the same surface form can point to different entities.
NED1
Entity disambiguation (via context triple)
gpt-5-mini-2025-08-07
Target entity: CRM197 diphtheria protein Context triple: [Prevnar 13, isConjugatedTo, CRM197 diphtheria protein]
-
A.
Corynebacterium diphtheriae
Corynebacterium diphtheriae is a Gram-positive, toxin-producing bacterium that causes the infectious disease diphtheria in humans.
-
B.
diphtheria antitoxin
Diphtheria antitoxin is a serum-based immune therapy that neutralizes the toxin produced by Corynebacterium diphtheriae, used to treat and prevent the severe complications of diphtheria infection.
-
C.
diphtheria
Diphtheria is a serious, potentially life-threatening infectious disease caused by Corynebacterium diphtheriae, characterized by sore throat, fever, and a thick gray membrane in the throat that can obstruct breathing.
-
D.
Streptomyces phage phiC31
Streptomyces phage phiC31 is a bacteriophage whose site-specific integrase has become a widely used tool for stable genome engineering in bacteria, plants, and animals.
-
E.
Serpins
Serpins is a civil parish in the municipality of Lousã in central Portugal, known for its natural landscapes and proximity to the Serra da Lousã.
- F. None of above. chosen
- G. Unsure - the case is ambiguous/there is not enough information to decide.
NED2
Entity disambiguation (via description)
gpt-5-mini-2025-08-07
Target entity: CRM197 diphtheria protein Target entity description: CRM197 diphtheria protein is a non-toxic mutant form of diphtheria toxin widely used as a carrier protein in conjugate vaccines to enhance immune responses to attached polysaccharide antigens.
-
A.
Corynebacterium diphtheriae
Corynebacterium diphtheriae is a Gram-positive, toxin-producing bacterium that causes the infectious disease diphtheria in humans.
-
B.
diphtheria antitoxin
Diphtheria antitoxin is a serum-based immune therapy that neutralizes the toxin produced by Corynebacterium diphtheriae, used to treat and prevent the severe complications of diphtheria infection.
-
C.
diphtheria
Diphtheria is a serious, potentially life-threatening infectious disease caused by Corynebacterium diphtheriae, characterized by sore throat, fever, and a thick gray membrane in the throat that can obstruct breathing.
-
D.
Streptomyces phage phiC31
Streptomyces phage phiC31 is a bacteriophage whose site-specific integrase has become a widely used tool for stable genome engineering in bacteria, plants, and animals.
-
E.
Serpins
Serpins is a civil parish in the municipality of Lousã in central Portugal, known for its natural landscapes and proximity to the Serra da Lousã.
- F. None of above. chosen
Referenced by (1)
Full triples — surface form annotated when it differs from this entity's canonical label.