Frizzled receptor
E1342629
UNEXPLORED
Frizzled receptors are a family of G protein–coupled receptor-like proteins that serve as primary cell-surface receptors for Wnt signaling, regulating key processes in development and cell fate determination.
All labels observed (2)
| Label | Occurrences |
|---|---|
| Class F frizzled receptors | 1 |
| Frizzled receptor canonical | 1 |
How this entity was disambiguated
This entity first appeared as the object of triple T18784337 — resolving that mention is where its identity was fixed. The disambiguator weighed these candidate entities and picked the highlighted one (or “None”, minting a new entity). This is how homonymy is resolved: the same surface form can point to different entities.
NED1
Entity disambiguation (via context triple)
gpt-5-mini-2025-08-07
Target entity: Frizzled receptor Context triple: [wingless, hasPathwayComponent, Frizzled receptor]
-
A.
Ephrin-B3
Ephrin-B3 is a transmembrane ligand of the Eph family of receptor tyrosine kinases that plays key roles in nervous system development and also serves as an entry receptor for certain henipaviruses.
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B.
Ephrin-B2
Ephrin-B2 is a cell surface ligand involved in developmental signaling that also serves as a critical entry receptor for several pathogenic viruses, including Hendra virus.
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C.
ERBB4
ERBB4 is a receptor tyrosine kinase of the ErbB/EGFR family involved in cell signaling pathways that regulate cell growth, differentiation, and development.
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D.
Sox2
Sox2 is a key transcription factor that maintains stem cell pluripotency and self-renewal and is widely used in cellular reprogramming.
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E.
Ezrin
Ezrin is a Canadian music producer and songwriter best known for his work on landmark rock albums by artists such as Pink Floyd, Alice Cooper, and Kiss.
- F. None of above. chosen
- G. Unsure - the case is ambiguous/there is not enough information to decide.
NED2
Entity disambiguation (via description)
gpt-5-mini-2025-08-07
Target entity: Frizzled receptor Target entity description: Frizzled receptors are a family of G protein–coupled receptor-like proteins that serve as primary cell-surface receptors for Wnt signaling, regulating key processes in development and cell fate determination.
-
A.
Ephrin-B3
Ephrin-B3 is a transmembrane ligand of the Eph family of receptor tyrosine kinases that plays key roles in nervous system development and also serves as an entry receptor for certain henipaviruses.
-
B.
Ephrin-B2
Ephrin-B2 is a cell surface ligand involved in developmental signaling that also serves as a critical entry receptor for several pathogenic viruses, including Hendra virus.
-
C.
ERBB4
ERBB4 is a receptor tyrosine kinase of the ErbB/EGFR family involved in cell signaling pathways that regulate cell growth, differentiation, and development.
-
D.
Sox2
Sox2 is a key transcription factor that maintains stem cell pluripotency and self-renewal and is widely used in cellular reprogramming.
-
E.
Ezrin
Ezrin is a Canadian music producer and songwriter best known for his work on landmark rock albums by artists such as Pink Floyd, Alice Cooper, and Kiss.
- F. None of above. chosen
Referenced by (2)
Full triples — surface form annotated when it differs from this entity's canonical label.
linked to: Frizzled receptor