Wnt1
E1342628
UNEXPLORED
Wnt1 is a highly conserved signaling protein in the Wnt family that plays a crucial role in embryonic development, cell fate determination, and oncogenesis in vertebrates.
All labels observed (1)
| Label | Occurrences |
|---|---|
| Wnt1 canonical | 1 |
How this entity was disambiguated
This entity first appeared as the object of triple T18784310 — resolving that mention is where its identity was fixed. The disambiguator weighed these candidate entities and picked the highlighted one (or “None”, minting a new entity). This is how homonymy is resolved: the same surface form can point to different entities.
NED1
Entity disambiguation (via context triple)
gpt-5-mini-2025-08-07
Target entity: Wnt1 Context triple: [wingless, orthologOf, Wnt1]
-
A.
Sox2
Sox2 is a key transcription factor that maintains stem cell pluripotency and self-renewal and is widely used in cellular reprogramming.
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B.
Hoxa
Hoxa is a small settlement on the Orkney island of South Ronaldsay in Scotland, known for its coastal setting and nearby historic sites.
-
C.
c-Myc
c-Myc is a proto-oncogene transcription factor that regulates cell growth, proliferation, and metabolism and is frequently dysregulated in cancer.
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D.
ERBB4
ERBB4 is a receptor tyrosine kinase of the ErbB/EGFR family involved in cell signaling pathways that regulate cell growth, differentiation, and development.
-
E.
Ephrin-B3
Ephrin-B3 is a transmembrane ligand of the Eph family of receptor tyrosine kinases that plays key roles in nervous system development and also serves as an entry receptor for certain henipaviruses.
- F. None of above. chosen
- G. Unsure - the case is ambiguous/there is not enough information to decide.
NED2
Entity disambiguation (via description)
gpt-5-mini-2025-08-07
Target entity: Wnt1 Target entity description: Wnt1 is a highly conserved signaling protein in the Wnt family that plays a crucial role in embryonic development, cell fate determination, and oncogenesis in vertebrates.
-
A.
Sox2
Sox2 is a key transcription factor that maintains stem cell pluripotency and self-renewal and is widely used in cellular reprogramming.
-
B.
Hoxa
Hoxa is a small settlement on the Orkney island of South Ronaldsay in Scotland, known for its coastal setting and nearby historic sites.
-
C.
c-Myc
c-Myc is a proto-oncogene transcription factor that regulates cell growth, proliferation, and metabolism and is frequently dysregulated in cancer.
-
D.
ERBB4
ERBB4 is a receptor tyrosine kinase of the ErbB/EGFR family involved in cell signaling pathways that regulate cell growth, differentiation, and development.
-
E.
Ephrin-B3
Ephrin-B3 is a transmembrane ligand of the Eph family of receptor tyrosine kinases that plays key roles in nervous system development and also serves as an entry receptor for certain henipaviruses.
- F. None of above. chosen
Referenced by (1)
Full triples — surface form annotated when it differs from this entity's canonical label.