transthyretin
E1294467
UNEXPLORED
Transthyretin is a transport protein primarily produced in the liver that carries thyroid hormones and retinol-binding protein, and whose misfolding and aggregation are implicated in hereditary and wild-type amyloid diseases.
All labels observed (1)
| Label | Occurrences |
|---|---|
| transthyretin canonical | 1 |
How this entity was disambiguated
This entity first appeared as the object of triple T17871611 — resolving that mention is where its identity was fixed. The disambiguator weighed these candidate entities and picked the highlighted one (or “None”, minting a new entity). This is how homonymy is resolved: the same surface form can point to different entities.
NED1
Entity disambiguation (via context triple)
gpt-5-mini-2025-08-07
Target entity: transthyretin Context triple: [Amvuttra, hasMolecularTarget, transthyretin]
-
A.
PTH
PTH is the station code for Perth railway station, a major central rail hub in Perth, Western Australia.
-
B.
light chain amyloidosis
Light chain amyloidosis is a rare systemic disorder in which misfolded immunoglobulin light chains form amyloid deposits in organs such as the heart and kidneys, leading to progressive organ dysfunction.
-
C.
Kayser-Roth
Kayser-Roth is an American apparel and hosiery company best known for brands like No Nonsense and its role as a major manufacturer of socks and legwear.
-
D.
HFE
HFE is the IATA airport code for Hefei Xinqiao International Airport, serving the city of Hefei in eastern China.
-
E.
Hipple
Hipple is the birth surname of American film and television actor Hugh Marlowe.
- F. None of above. chosen
- G. Unsure - the case is ambiguous/there is not enough information to decide.
NED2
Entity disambiguation (via description)
gpt-5-mini-2025-08-07
Target entity: transthyretin Target entity description: Transthyretin is a transport protein primarily produced in the liver that carries thyroid hormones and retinol-binding protein, and whose misfolding and aggregation are implicated in hereditary and wild-type amyloid diseases.
-
A.
PTH
PTH is the station code for Perth railway station, a major central rail hub in Perth, Western Australia.
-
B.
light chain amyloidosis
Light chain amyloidosis is a rare systemic disorder in which misfolded immunoglobulin light chains form amyloid deposits in organs such as the heart and kidneys, leading to progressive organ dysfunction.
-
C.
Kayser-Roth
Kayser-Roth is an American apparel and hosiery company best known for brands like No Nonsense and its role as a major manufacturer of socks and legwear.
-
D.
HFE
HFE is the IATA airport code for Hefei Xinqiao International Airport, serving the city of Hefei in eastern China.
-
E.
Hipple
Hipple is the birth surname of American film and television actor Hugh Marlowe.
- F. None of above. chosen
Referenced by (1)
Full triples — surface form annotated when it differs from this entity's canonical label.