RNA-dependent RNA polymerase L
E1249840
UNEXPLORED
RNA-dependent RNA polymerase L is the large catalytic enzyme of Ebolavirus responsible for replicating and transcribing the viral RNA genome.
All labels observed (1)
| Label | Occurrences |
|---|---|
| RNA-dependent RNA polymerase L canonical | 2 |
How this entity was disambiguated
This entity first appeared as the object of triple T17092999 — resolving that mention is where its identity was fixed. The disambiguator weighed these candidate entities and picked the highlighted one (or “None”, minting a new entity). This is how homonymy is resolved: the same surface form can point to different entities.
NED1
Entity disambiguation (via context triple)
gpt-5-mini-2025-08-07
Target entity: RNA-dependent RNA polymerase L Context triple: [Ebolavirus, protein, RNA-dependent RNA polymerase L]
-
A.
HCV NS5B RNA-dependent RNA polymerase
HCV NS5B RNA-dependent RNA polymerase is the viral enzyme in hepatitis C virus responsible for replicating its RNA genome and a key target for direct-acting antiviral drugs.
-
B.
SARS-CoV-2 RNA-dependent RNA polymerase
SARS-CoV-2 RNA-dependent RNA polymerase is the key viral enzyme responsible for replicating the coronavirus’s RNA genome and is a primary target for antiviral drugs such as remdesivir.
-
C.
HCV NS5A protein
HCV NS5A protein is a multifunctional nonstructural hepatitis C virus protein essential for viral RNA replication and assembly, and a key target of several direct-acting antiviral drugs.
-
D.
Mastadenovirus
Mastadenovirus is a genus of non-enveloped, double-stranded DNA viruses in the Adenoviridae family that infect mammals, including humans, and are associated with a range of respiratory, ocular, and gastrointestinal diseases.
-
E.
RNA polymerase II
RNA polymerase II is the eukaryotic enzyme complex responsible for transcribing DNA into messenger RNA and many non-coding RNAs, playing a central role in gene expression.
- F. None of above. chosen
- G. Unsure - the case is ambiguous/there is not enough information to decide.
NED2
Entity disambiguation (via description)
gpt-5-mini-2025-08-07
Target entity: RNA-dependent RNA polymerase L Target entity description: RNA-dependent RNA polymerase L is the large catalytic enzyme of Ebolavirus responsible for replicating and transcribing the viral RNA genome.
-
A.
HCV NS5B RNA-dependent RNA polymerase
HCV NS5B RNA-dependent RNA polymerase is the viral enzyme in hepatitis C virus responsible for replicating its RNA genome and a key target for direct-acting antiviral drugs.
-
B.
SARS-CoV-2 RNA-dependent RNA polymerase
SARS-CoV-2 RNA-dependent RNA polymerase is the key viral enzyme responsible for replicating the coronavirus’s RNA genome and is a primary target for antiviral drugs such as remdesivir.
-
C.
HCV NS5A protein
HCV NS5A protein is a multifunctional nonstructural hepatitis C virus protein essential for viral RNA replication and assembly, and a key target of several direct-acting antiviral drugs.
-
D.
Mastadenovirus
Mastadenovirus is a genus of non-enveloped, double-stranded DNA viruses in the Adenoviridae family that infect mammals, including humans, and are associated with a range of respiratory, ocular, and gastrointestinal diseases.
-
E.
RNA polymerase II
RNA polymerase II is the eukaryotic enzyme complex responsible for transcribing DNA into messenger RNA and many non-coding RNAs, playing a central role in gene expression.
- F. None of above. chosen
Referenced by (2)
Full triples — surface form annotated when it differs from this entity's canonical label.