Corey– Ziegler– Seebach reaction
GPTKB entity
Statements (60)
| Predicate | Object |
|---|---|
| gptkbp:instance_of |
gptkb:chemical_compound
|
| gptkbp:bfsLayer |
5
|
| gptkbp:bfsParent |
gptkb:E._J._Corey
|
| gptkbp:applies_to |
aldehydes
ketones |
| gptkbp:developed_by |
1970s
|
| https://www.w3.org/2000/01/rdf-schema#label |
Corey– Ziegler– Seebach reaction
|
| gptkbp:involves |
nucleophilic attack
protonation silyl enol ethers deprotonation |
| gptkbp:is_used_in |
material science
pharmaceutical chemistry |
| gptkbp:named_after |
gptkb:E._J._Corey
gptkb:H._Ziegler W. Seebach |
| gptkbp:produced_by |
α,β-unsaturated carbonyl compounds
|
| gptkbp:related_to |
aldol reaction
Michael addition |
| gptkbp:requires |
base catalyst
|
| gptkbp:significance |
asymmetric synthesis
|
| gptkbp:technique |
synthesis of complex molecules
functionalization of alkenes stereoselective synthesis preparation of enals preparation of enones preparation of α,β-unsaturated aldehydes preparation of α,β-unsaturated amides preparation of α,β-unsaturated benzimidazoles preparation of α,β-unsaturated benzothiazoles preparation of α,β-unsaturated benzoxazoles preparation of α,β-unsaturated boronates preparation of α,β-unsaturated esters preparation of α,β-unsaturated furans preparation of α,β-unsaturated germanes preparation of α,β-unsaturated imidazoles preparation of α,β-unsaturated indoles preparation of α,β-unsaturated isoquinolines preparation of α,β-unsaturated ketones preparation of α,β-unsaturated nitriles preparation of α,β-unsaturated oxazoles preparation of α,β-unsaturated phosphine oxides preparation of α,β-unsaturated phosphonates preparation of α,β-unsaturated pyrazoles preparation of α,β-unsaturated pyridines preparation of α,β-unsaturated pyrimidines preparation of α,β-unsaturated pyrroles preparation of α,β-unsaturated quinolines preparation of α,β-unsaturated selenides preparation of α,β-unsaturated silanes preparation of α,β-unsaturated stannanes preparation of α,β-unsaturated sulfones preparation of α,β-unsaturated sulfoxides preparation of α,β-unsaturated tellurides preparation of α,β-unsaturated thiazoles preparation of α,β-unsaturated thioesters preparation of α,β-unsaturated thiophenes |
| gptkbp:type |
organic synthesis
|
| gptkbp:type_of |
carbon-carbon bond formation
|
| gptkbp:used_in |
total synthesis of natural products
|