Corey– Ziegler– Hoffmann reaction

GPTKB entity

Statements (53)
Predicate Object
gptkbp:instance_of gptkb:chemical_compound
gptkbp:bfsLayer 5
gptkbp:bfsParent gptkb:Elias_James_Corey
gptkb:E._J._Corey
gptkbp:applies_to pharmaceutical chemistry
ketones
chemical industry
gptkbp:can_lead_to new carbon-carbon bonds
gptkbp:developed_by 1970s
https://www.w3.org/2000/01/rdf-schema#label Corey– Ziegler– Hoffmann reaction
gptkbp:ingredients gptkb:sodium_bromide
gptkb:sodium_hypochlorite
acetic acid
gptkbp:involves oxidation
gptkbp:is_associated_with E. J. Corey’s work
gptkbp:is_considered a key reaction in organic synthesis
a versatile reaction
a foundational reaction
gptkbp:is_documented_in gptkb:literary_work
gptkbp:is_explored_in research studies
new applications
gptkbp:is_influenced_by reaction conditions
gptkbp:is_noted_for selectivity
its selectivity and efficiency
gptkbp:is_optimized_for yield
gptkbp:is_part_of organic chemistry
reaction mechanisms
reaction pathways
synthetic methodology
gptkbp:is_recognized_for its efficiency
gptkbp:is_related_to Wittig reaction
oxidative cleavage
functionalization of hydrocarbons
gptkbp:is_studied_in mechanistic chemistry
mechanistic insights
gptkbp:is_used_by aldehydes from alcohols
gptkbp:is_used_for functional group transformations
convert alcohols to aldehydes
gptkbp:is_used_in synthesis of complex molecules
synthesis of natural products
synthesis of intermediates
gptkbp:is_utilized_in gptkb:academic_research
synthesis of complex structures
gptkbp:named_after gptkb:E._J._Corey
gptkb:H._Ziegler
gptkb:R._Hoffmann
gptkbp:performed_by various substrates
gptkbp:produced_by aldehydes
gptkbp:significance total synthesis
gptkbp:training organic chemistry courses
gptkbp:type organic synthesis
gptkbp:uses gptkb:lithium_diisopropylamide
gptkbp:was_a_catalyst_for copper salts