Statements (55)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
chemical reaction
|
| gptkbp:appliesTo |
synthesis of complex molecules
|
| gptkbp:can_be |
mild conditions
stereochemically_complex_molecules |
| gptkbp:formed |
C-C bonds
|
| gptkbp:hasPrograms |
material science
|
| https://www.w3.org/2000/01/rdf-schema#label |
Corey–Lythgoe reaction
|
| gptkbp:influenced |
electronic factors
steric_factors |
| gptkbp:involves |
alkenes
|
| gptkbp:is_a |
nucleophilic substitution
|
| gptkbp:is_a_subject_of |
synthesis pathways
|
| gptkbp:is_a_time_for |
functional group transformation
|
| gptkbp:is_characterized_by |
high selectivity
|
| gptkbp:is_essential_for |
carbon chain elongation
|
| gptkbp:is_studied_in |
organic chemistry
|
| gptkbp:is_used_in |
academic research
pharmaceutical chemistry other alkylation methods |
| gptkbp:leads |
chiral centers
|
| gptkbp:namedAfter |
gptkb:E.J._Corey
Lythgoe |
| gptkbp:produces |
20th century
alkylated products |
| gptkbp:related_to |
cross-coupling reactions
|
| gptkbp:requires |
specific reaction conditions
|
| gptkbp:suitableFor |
natural product synthesis
|
| gptkbp:type |
organic synthesis
|
| gptkbp:utilizes |
lithium_reagents
|
| gptkbp:was_a_response_to |
can be optimized
involves multiple steps can be performed in solution can be scaled up can be catalyzed can be performed under anhydrous conditions can be performed at room temperature can be performed in the presence of acids can be performed in the presence of additives can be performed in the presence of bases can be performed in the presence of catalysts can be performed in the presence of ligands can be performed in the presence of solvents can be performed under reflux conditions can be monitored by spectroscopy can be performed in the presence of reagents can produce side products requires purification steps can be performed in the presence of solvents and acids can be performed in the presence of solvents and additives can be performed in the presence of protecting groups can be performed in the presence of solvents and ligands can be performed in the presence of solvents and bases can be performed in the presence of solvents and reagents can be performed in the presence of solvents and catalysts can be performed in the presence of solvents and protecting groups |