Statements (46)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
chemical reaction
|
| gptkbp:appearsIn |
material science
pharmaceutical chemistry natural product synthesis |
| gptkbp:benefits |
high yield
versatility limited substrate scope mild reaction conditions potential for side reactions sensitive to moisture requires strong bases |
| gptkbp:category |
rearrangement reaction
|
| gptkbp:citedBy |
widely cited in literature
discussed in research articles featured in reviews found in textbooks |
| gptkbp:developedBy |
gptkb:Robert_Lind
gptkb:Elias_J._Corey |
| gptkbp:field |
medicinal chemistry
industrial chemistry synthetic organic chemistry |
| gptkbp:firstPublished |
1960s
|
| gptkbp:historicalSignificance |
contributed to modern organic synthesis
influenced synthetic methodologies recognized in retrosynthetic analysis |
| https://www.w3.org/2000/01/rdf-schema#label |
Corey–Lind reaction
|
| gptkbp:internationalClassification |
low temperature
anhydrous conditions substitution reaction controlled atmosphere non-aqueous solvent |
| gptkbp:involves |
alkyl halides
carbonyl compounds lithium diisopropylamide |
| gptkbp:notableFor |
selectivity in synthesis
|
| gptkbp:produces |
α,β-unsaturated carbonyl compounds
|
| gptkbp:relatedTo |
aldol reaction
Grignard_reaction |
| gptkbp:requires |
strong base
|
| gptkbp:safetyFeatures |
handle with care
avoid inhalation of vapors store chemicals properly use_appropriate_PPE |
| gptkbp:triggerType |
nucleophilic substitution
|
| gptkbp:type |
organic synthesis
|
| gptkbp:usedFor |
synthesis of aldehydes
|