Statements (50)
Predicate | Object |
---|---|
gptkbp:instanceOf |
chemical reaction
|
gptkbp:allows |
functional group tolerance
|
gptkbp:appliesTo |
organic synthesis
polymer chemistry |
gptkbp:can_be |
mild conditions
|
gptkbp:enhances |
reaction efficiency
|
gptkbp:firstPublished |
1982
|
gptkbp:formed |
C-C bonds
|
https://www.w3.org/2000/01/rdf-schema#label |
Corey–House coupling
|
gptkbp:influenced |
synthetic methodologies
|
gptkbp:internationalClassification |
cross-coupling reaction
|
gptkbp:involves |
lithium_diorganocopper_reagents
|
gptkbp:is_a |
carbon-carbon bond formation
|
gptkbp:is_a_subject_of |
total synthesis
|
gptkbp:is_a_time_for |
forming carbon-carbon bonds
|
gptkbp:is_a_tool_for |
alkene formation
|
gptkbp:is_essential_for |
modern organic chemistry
material science applications |
gptkbp:is_integrated_with |
automated synthesis platforms
|
gptkbp:is_studied_in |
academic research
mechanistic insights. |
gptkbp:is_used_in |
gptkb:Negishi_coupling
pharmaceutical synthesis complex molecules aryl halides other coupling reactions |
gptkbp:modifications |
existing compounds
|
gptkbp:previousName |
E._J._Corey_and_H._House
|
gptkbp:produces |
gptkb:E._J._Corey
substituted alkenes |
gptkbp:related_to |
Sonogashira_coupling
|
gptkbp:requires |
copper catalyst
|
gptkbp:suitableFor |
various substrates
|
gptkbp:usedFor |
alkenes
|
gptkbp:was_a_catalyst_for |
industrial applications
environmental sustainability natural products yield and selectivity new catalyst development |
gptkbp:was_a_response_to |
asymmetric synthesis
green chemistry principles high regioselectivity bioconjugation strategies one-pot procedures stereoselective products low catalyst loadings heterocyclic compounds drug discovery processes diverse chemical environments organocuprates_and_electrophiles |