Corey–House coupling

GPTKB entity

Statements (50)
Predicate Object
gptkbp:instanceOf chemical reaction
gptkbp:allows functional group tolerance
gptkbp:appliesTo organic synthesis
polymer chemistry
gptkbp:can_be mild conditions
gptkbp:enhances reaction efficiency
gptkbp:firstPublished 1982
gptkbp:formed C-C bonds
https://www.w3.org/2000/01/rdf-schema#label Corey–House coupling
gptkbp:influenced synthetic methodologies
gptkbp:internationalClassification cross-coupling reaction
gptkbp:involves lithium_diorganocopper_reagents
gptkbp:is_a carbon-carbon bond formation
gptkbp:is_a_subject_of total synthesis
gptkbp:is_a_time_for forming carbon-carbon bonds
gptkbp:is_a_tool_for alkene formation
gptkbp:is_essential_for modern organic chemistry
material science applications
gptkbp:is_integrated_with automated synthesis platforms
gptkbp:is_studied_in academic research
mechanistic insights.
gptkbp:is_used_in gptkb:Negishi_coupling
pharmaceutical synthesis
complex molecules
aryl halides
other coupling reactions
gptkbp:modifications existing compounds
gptkbp:previousName E._J._Corey_and_H._House
gptkbp:produces gptkb:E._J._Corey
substituted alkenes
gptkbp:related_to Sonogashira_coupling
gptkbp:requires copper catalyst
gptkbp:suitableFor various substrates
gptkbp:usedFor alkenes
gptkbp:was_a_catalyst_for industrial applications
environmental sustainability
natural products
yield and selectivity
new catalyst development
gptkbp:was_a_response_to asymmetric synthesis
green chemistry principles
high regioselectivity
bioconjugation strategies
one-pot procedures
stereoselective products
low catalyst loadings
heterocyclic compounds
drug discovery processes
diverse chemical environments
organocuprates_and_electrophiles