Statements (51)
Predicate | Object |
---|---|
gptkbp:instanceOf |
medication
|
gptkbp:activeDuring |
sulfasalazine
|
gptkbp:brand |
gptkb:Azulfidine
|
gptkbp:clinicalTrials |
pediatric use
long-term safety combination therapy with methotrexate comparison with mesalamine efficacy in rheumatoid arthritis efficacy in ulcerative colitis |
gptkbp:contraindication |
porphyria
liver toxicity kidney damage severe liver disease severe renal impairment intestinal obstruction sulfa allergy bone_marrow_suppression |
gptkbp:date |
FDA_approved
|
gptkbp:dosageForm |
tablet
|
gptkbp:drugInterdiction |
true
anti-inflammatory |
gptkbp:endOfLife |
7 to 12 hours
|
gptkbp:formulation |
enteric-coated tablet
|
gptkbp:gestationPeriod |
Category B
|
gptkbp:healthcare |
liver function tests
complete blood count renal function tests |
https://www.w3.org/2000/01/rdf-schema#label |
Azulfidine EN-tabs
|
gptkbp:interactsWith |
warfarin
methotrexate azathioprine |
gptkbp:lastProduced |
1968
|
gptkbp:mandates |
Crohn's disease
|
gptkbp:manufacturer |
gptkb:Pfizer
|
gptkbp:nutritionalValue |
liver
|
gptkbp:packaging |
bottle
|
gptkbp:route |
oral
|
gptkbp:sideEffect |
headache
nausea diarrhea rash |
gptkbp:skills |
500 mg
|
gptkbp:storage |
room temperature
|
gptkbp:threats |
asthma
hypersensitivity reactions G6PD deficiency |
gptkbp:triggerType |
inhibits leukotriene synthesis
|
gptkbp:type |
sulfasalazine
|
gptkbp:usedFor |
treatment of rheumatoid arthritis
treatment of ulcerative colitis |
gptkbp:waterManagement |
urine
|