Atypical Hemolytic Uremic Syndrome
GPTKB entity
Statements (59)
| Predicate | Object |
|---|---|
| gptkbp:instance_of |
gptkb:healthcare_organization
|
| gptkbp:affects |
gptkb:Person
Adults |
| gptkbp:can_be |
Neurological complications
|
| gptkbp:can_lead_to |
Hypertension
Long-term kidney damage |
| gptkbp:caused_by |
Kidney failure
Severe abdominal pain |
| gptkbp:current_use |
Can be life-threatening
Affects the blood vessels Can recur after treatment May require kidney transplantation Requires ongoing management Requires prompt treatment |
| gptkbp:family |
gptkb:theorem
|
| gptkbp:has_a |
Variable
|
| gptkbp:has_achievements |
Infections
|
| https://www.w3.org/2000/01/rdf-schema#label |
Atypical Hemolytic Uremic Syndrome
|
| gptkbp:is_affected_by |
Infants
|
| gptkbp:is_aimed_at |
Infections
Genetic mutations |
| gptkbp:is_associated_with |
Diarrhea
Autoimmune diseases Pregnancy complications Chronic kidney disease Thrombotic thrombocytopenic purpura Complement system dysregulation Microangiopathic hemolytic anemia |
| gptkbp:is_characterized_by |
Hemolytic anemia
Thrombocytopenia Acute renal failure Elevated creatinine levels Elevated lactate dehydrogenase Low haptoglobin levels |
| gptkbp:is_influenced_by |
Environmental factors
|
| gptkbp:is_linked_to |
gptkb:Factor_H_mutations
gptkb:Factor_I_mutations MCP mutations |
| gptkbp:is_monitored_by |
Regular blood tests
|
| gptkbp:is_often_used_in |
gptkb:Typical_Hemolytic_Uremic_Syndrome
Females |
| gptkbp:is_part_of |
Thrombotic microangiopathies
|
| gptkbp:is_recognized_by |
gptkb:hospital
|
| gptkbp:is_studied_in |
Clinical research
|
| gptkbp:managed_by |
Multidisciplinary teams
|
| gptkbp:requires |
Dialysis
|
| gptkbp:scientific_classification |
A rare disease
|
| gptkbp:social_responsibility |
Blood tests
Clinical evaluation Urinalysis Kidney biopsy |
| gptkbp:treatment |
Supportive care
Immunosuppressive therapy Nephrologists Complement inhibitors Plasma exchange |
| gptkbp:type_of |
Thrombotic microangiopathy
|
| gptkbp:bfsParent |
gptkb:Ravulizumab
|
| gptkbp:bfsLayer |
7
|