Statements (72)
| Predicate | Object |
|---|---|
| gptkbp:instance_of |
gptkb:pharmaceuticals
|
| gptkbp:approves |
gptkb:FDA
|
| gptkbp:available_in |
various strengths
|
| gptkbp:clinical_trial |
donepezil efficacy study
donepezil safety study |
| gptkbp:clinical_use |
mild to moderate Alzheimer's disease
severe Alzheimer's disease |
| gptkbp:contraindication |
allergy to donepezil
|
| gptkbp:dosage_form |
gptkb:tablet
|
| gptkbp:duration |
long-term use
|
| gptkbp:effect_on_behavior |
may reduce behavioral symptoms
|
| gptkbp:effect_on_cognition |
improves cognitive function
|
| gptkbp:effect_on_daily_living |
improves daily living activities
|
| gptkbp:financial_support |
do not crush or chew
take at bedtime allow to dissolve on tongue |
| gptkbp:formulation |
orally disintegrating tablet
|
| https://www.w3.org/2000/01/rdf-schema#label |
Aricept ODT
|
| gptkbp:ingredients |
gptkb:donepezil
|
| gptkbp:interacts_with |
beta-blockers
nonsteroidal anti-inflammatory drugs (NSAIDs) anticholinergic drugs |
| gptkbp:manufacturer |
gptkb:Eisai_Co.,_Ltd.
|
| gptkbp:marketed_as |
gptkb:1996
|
| gptkbp:packaging |
blister pack
|
| gptkbp:requires |
gptkb:true
|
| gptkbp:research |
donepezil and adverse events
donepezil and amyloid plaques donepezil and biomarkers donepezil and caregiver burden donepezil and cholinergic system donepezil and cognitive decline donepezil and cognitive reserve donepezil and comorbidities donepezil and cost-effectiveness donepezil and environmental factors donepezil and functional decline donepezil and genetic factors donepezil and health outcomes donepezil and inflammation donepezil and lifestyle factors donepezil and long-term safety donepezil and mental health donepezil and neuroinflammation donepezil and neuroprotection donepezil and neuropsychiatric symptoms donepezil and overall well-being donepezil and oxidative stress donepezil and patient adherence donepezil and patient satisfaction donepezil and physical health donepezil and quality of life donepezil and social support donepezil and synaptic function donepezil and synaptic plasticity donepezil and tau pathology donepezil and treatment response donepezil combination therapy donepezil in elderly patients donepezil long-term effects donepezil pharmacodynamics donepezil pharmacokinetics |
| gptkbp:route_of_administration |
oral
|
| gptkbp:side_effect |
fatigue
nausea diarrhea insomnia muscle cramps |
| gptkbp:storage |
room temperature
|
| gptkbp:used_for |
gptkb:neurodegenerative_diseases
|
| gptkbp:bfsParent |
gptkb:Aricept
|
| gptkbp:bfsLayer |
6
|